The new proposed AdminPatch system is a microneedle transdermal delivery technology that forms hundreds of tiny aqueous channels (micropores) through the skin. Proteins and water-soluble molecules can enter the body through these aqueous micropores. The punch holes or created aqueous channels stay open while AdminPatch is applied through the skin.
The AdminPatch system can be a single-use disposable unit - or a re-useable handheld Applicator. The disposable AdminPatch contains a proprietary microneedle array laminated on a conventional transdermal drug-in-adhesive patch.
AdminPatch is based on the proprietary microneedle shape which has been developed by nanoBioSciences LLC. The proprietary microneedle shape allows continuous delivery of drugs when the microneedle is inserted in the skin. The microneedles are formed from a standard metal film. A conventional transdermal drug-in-adhesive patch is laminated on the back surface of the microneedles.
The aqueous channels formed by the microneedles have a depth of about 100 microns, deep enough to extend through the viable epidermis but shallow enough to avoid the dermis and any pain receptors.
When the transdermal patch is removed from the skin, the micropores simply collapse and the skin barrier repairs itself.
No comments:
Post a Comment